CAS:479633-63-1|4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine

Catalogue Number:C370130
Chemical Name:4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine
Synonyms:4-Chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-7-(4-methylphenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine;
CAS Number:479633-63-1
Molecular Formula:C₁₃H₁₀ClN₃O₂S
Appearance:White to Off-White Solid
Melting Point:147 – 149°C
Molecular Weight:307.76
Storage:4°C, Inert atmosphere
Solubility:Chloroform (Slightly), DMSO (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine is a reagent in the synthesis of (+)-tofacitinib, a selective Janus kinase 3 inhibitor (JAK3) and an immunosuppressant drug.
References:Liao, H., et al.: Tetrahedron: Asymmetry, 28, 105, (2017)
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