CAS:4834-35-9|Benz[a]anthracen-3-ol

Catalogue Number:B120585
Chemical Name:Benz[a]anthracen-3-ol
Synonyms:3-Hydroxybenz[a]anthracene
CAS Number:4834-35-9
Molecular Formula:C₁₈H₁₂O
Appearance:Pale Beige to Beige Solid
Melting Point:212-215°C
Molecular Weight:244.29
Storage:4°C
Solubility:DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Benz[a]anthracen-3-ol is a derivative of the most potent carcinogenic hydrocarbon, 7,12-Dimethylbenz[a]anthracene (D464500), a highly potent carcinogen that is activated by microsomal enzymes to a diol epoxide metabolite that binds covalently to DNA in mammalian cells, leading ultimately to tumor induction. Benz[a]anthracen-3-ol is used in carcinogenesis studies relating to breast cancer.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References:Harvey, R. et al.: J. Org. Chem., 69, 2024 (2004); Harvey, R. et a;.: J. Med. Chem., 31, 154 (1988); Lee. H. et al.: J. Org. Chem., 51, 3501 (1986); Huggins, C., et al.: Proc. Nat. Acad. Sci. U.S.A., 58, 2253 (1967), Dipple, A., et al.: N. Cancer Res., 43, 4123 (1983);
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