Catalogue Number:C696280
Chemical Name:a-Cortolone
Synonyms:3α,17,20α,21-Tetrahydroxy-5β-pregnan-11-one; 20α-Cortolone; 3α,17,20α,21-Tetrahydroxy-5β-pregnan-11-one; 3α,17α,20α,21-Tetrahydroxy-5β-pregnan-11-one; 5β-Pregnan-3α,17α,20α,21-tetrol-11-one; 5β-Pregnane-3α,17,20α,21-tetrol-11-one; 5β-Pregnane-3α,17α,20α,21-tetrol-11-one; Cortolon; Cortolone; NSC 59872
CAS Number:516-42-7
Molecular Formula:C₂₁H₃₄O₅
Appearance:White to Off-White Solid
Melting Point:>111°C (dec.)
Molecular Weight:366.49
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
Stability
Hygroscopic
Category:Standards; Chiral Molecules; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:a-Cortolone is a human urinary metabolite of Cortisol ((H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis
References:Yergey, A.L., et. al.: Steroids, 60, 295 (1995); Vigore, L., et al.: Cancer Ther., 6, 699 (2008);
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Posted inMaterials
CAS:516-42-7|a-Cortolone
