CAS:5334-31-6|5-Amino-4-pyrazolecarboxamide

Catalogue Number:A628745
Chemical Name:5-Amino-4-pyrazolecarboxamide
Synonyms:3-Amino-1H-pyrazole-4-carboxamide; 3-Amino-4-carbamoylpyrazole; 3-Amino-4-pyrazolecarboxamide; NSC 1402; Allopurinol EP Impurity A
Impurity:Allopurinol EP Impurity A
CAS Number:5334-31-6
Molecular Formula:C₄H₆N₄O
Appearance:Off-White to Pale Brown Solid
Melting Point:180-185°C
Molecular Weight:126.12
Storage:4°C
Solubility:DMSO (Soluble), Methanol (Slightly)
Category:Building Blocks; Miscellaneous;
Applications:5-Amino-4-pyrazolecarboxamide is used in the synthesis of 4H-3,1-Benzothiazinone analogs as antiproliferative agents against human cancer cell lines. Also, it is an intermediate used in the synthesis of 3-(4H-1,2,4-Triazol-4-yl)-1H-pyrazole-4-carboxamide (T767570), which is an impurity of Allopurinol (A547300), which is a xanthine oxidase inhibitor
References:Matysiak, J., et al.: Arab. J. Chem., (2015); Benezra, S.A., et al.: Anal. Profiles Drug Subs., 7, 1, (1978); Dalbeth, N., et al.: Rheumatology, 44, 1090 (2005); Dinarello, C., et al.: J. Exp. Med., 201, 1355 (2005);
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