CAS:54237-72-8|Cimetidine Sulfoxide

CAS:54237-72-8|Cimetidine Sulfoxide

Catalogue Number:C441680
Chemical Name:Cimetidine Sulfoxide
Synonyms:N-Cyano-N’-methyl-N”-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]sulfinyl]ethyl]guanidine; (±)-Cimetidine S-Oxide; SKF 92452; Cimetidine EP Impurity E
Impurity:Cimetidine EP Impurity E
CAS Number:54237-72-8
Molecular Formula:C₁₀H₁₆N₆OS
Appearance:White to Off-White Solid
Melting Point:>180°C (dec.)
Molecular Weight:268.34
Storage:-20°C
Solubility:DMSO (Slightly, Heated), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Cimetidine Sulfoxide (Cimetidine EP Impurity E) is a metabolite of the H2-receptor antagonist Cimetidine (C441650). Cimetidine Sulfoxide is detected in the blood and urine of patients with kidney diseases.
References:Luksa, J. et al.: J. Chrom. B Biomed. Appl., 667, 321 (1995); Lee, R.M. et al.: J. Chrom. Biomed. Appl., 146, 354 (1978);
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