CAS:549-18-8|Amitriptyline Hydrochloride

Catalogue Number:A633350
Chemical Name:Amitriptyline Hydrochloride
Synonyms:3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine Hydrochloride; Adepril; Amineurin; Domical; Elavil; Endep; Euplit; Laroxyl; Tryptanol; Tryptizol;
CAS Number:549-18-8
Alternate CAS #
Free Base: 50-48-6
Molecular Formula:C₂₀H₂₄ClN
Appearance:White to Pale Beige Solid
Melting Point:194-196°C
Molecular Weight:313.86
Storage:4°C
Solubility:Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Amitriptyline HCl is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References:1. Tobe, A., et al.: Arzneim.-Forsch., 31, 1278 (1981)
2. Jang, S. W., et al.: Chem Biol. 16, 644 (2009)
3. Fattahian, E. et al.: IJPR 15, 125 (2016)
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