CAS:5652-28-8|D,L-2-Amino-3-phosphonopropionic Acid

Catalogue Number:A627570
Chemical Name:D,L-2-Amino-3-phosphonopropionic Acid
Synonyms:3-Phosphonoalanine; (±)-2-Amino-3-phosphonopropanoic Acid; (±)-2-Amino-3-phosphonopropionic Acid; 2-Amino-3-phosphonopropionic Acid; 3-Phosphono-DL-alanine; DL-2-Amino-2-carboxyethylphosphonic Acid; DL-2-Amino-3-phosphonopropionate; NSC 30078; (2-Amino-2-carboxyethyl)phosphonic Acid; α-Amino-β-phosphonopropionic Acid
CAS Number:5652-28-8
Molecular Formula:C₃H₈NO₅P
Appearance:Pale Brown to Light Brown Solid
Melting Point:>213°C (dec.)
Molecular Weight:169.07
Storage:4°C
Solubility:Methanol (Slightly), Water (Slightly)
Stability
Hygroscopic
Category:Research Tools; Amino Acids; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:D,L-2-Amino-3-phosphonopropionic acid is a phosphonate substituted derivative of Aspartic acid (A788955) and is a known antagonist of a receptor that is coupled to phosphoinositide metabolism in brain slices. D,L-2-Amino-3-phosphonopropionic acid is also an inhibitor of metabotropic glutamate receptors in rat brain.
References:Hedberg, T. & Stanton, P.: Eur. J. Pharma., 310, 19 (1996); Saugstad, J., et al.: Eur. J. Pharm.: Mol. Pharm., 289, 395 (1995); Schoepp, D., et al.: Mol. Pharm., 38, 222 (1990)
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