CAS:571189-65-6|6-Desacetyl-N-Boc Palbociclib

Catalogue Number:D288713
Chemical Name:6-Desacetyl-N-Boc Palbociclib
Synonyms:4-[6-[(8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylic Acid tert-Butyl Ester
CAS Number:571189-65-6
Molecular Formula:C₂₇H₃₅N₇O₃
Appearance:White to Off-White Solid
Melting Point:>209°C (dec.)
Molecular Weight:505.61
Storage:4°C, Inert atmosphere
Solubility:Chloroform (Slightly), Methanol (Slightly, Heated), Dichloromethane
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:6-Desacetyl N-Boc Palbociclib is an impurity of Palbociclib (P139900),(also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
References:Finn, R., et al.: Breast Cancer Res., 11, 5 (2009);
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