CAS:58579-51-4|Anagrelide Hydrochloride

Catalogue Number:A637300
Chemical Name:Anagrelide Hydrochloride
Synonyms:6,7-Dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one; BL-4162A; BMY-26538-01; Agrylin; Tromboreductin; Xagrid; RL 603;
CAS Number:58579-51-4
Alternate CAS #
Free Base: 68475-42-3
Molecular Formula:C₁₀H₈Cl₃N₃O
Appearance:White to Light Beige Solid
Melting Point:>266°C (dec.)
Molecular Weight:292.55
Storage:-20°C
Solubility:Acetone (Slightly), DMSO (Slightly), Ethanol
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Anagrelide Hydrochloride is a phosphodiesterase inhibitor with antiplatelet activity. Used as an antithrombocythemic. Potent PDE3 inhibitor.
References:Fleming, J.S., et al.: Thromb. Res., 15, 373 (1979), Seiler, S., et al.: J. Pharmacol. Exp. Ther., 243, 767 (1984), Silverstein, M. N., et al.: N. Engl. J. Med., 318, 1292 (1988), Spencer, C.M., et al.: Drugs, 47, 809 (1994),
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