CAS:58814-71-4|Chenodeoxycholic Acid-3-b-D-glucuronide

Catalogue Number:C291920
Chemical Name:Chenodeoxycholic Acid-3-b-D-glucuronide
Synonyms:24-Norcholane, β-D-glucopyranosiduronic Acid Deriv.; Chenodeoxycholic Acid 3-Gucuronide; (3α,5β,7α)-23-Carboxy-7-hydroxy-24-norcholan-3-yl β-D-Glucopyranosiduronic Acid
CAS Number:58814-71-4
Molecular Formula:C₃₀H₄₈O₁₀
Appearance:White to Off-White Solid
Melting Point:>166°C (subl.)
Molecular Weight:568.7
Storage:4°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Stability
Hygroscopic
Category:Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Chenodeoxycholic acid-3-b-D-glucuronide is a derivative of chenodeoxycholic acid (C291900). Chenodeoxycholic acid is a major bile acid in many vertebrates, occurring as the N-glycine and/or N-taurine conjugate. With other bile acids, forms mixed micelles with lecithin in bile which solubilize cholesterol and thus facilitates its excretion. Fcilitates fat absorption in the small intestine by micellar solubilization of fatty acids and monoglycerides. Anticholelithogenic. Epimeric with Ursodiol.
References:Danzinger, et al.: N. Engl. J. Med., 286, 1 (1972), Iser, J.H., et al.: Drugs, 21, 90 (1981), Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986),
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