CAS:5928-25-6|Decursin

CAS:5928-25-6|Decursin

Catalogue Number:D226918
Chemical Name:Decursin
Synonyms:(7S)-7,8-Dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b’]dipyran-7-yl 3-Methyl-2-Butenoic Acid Ester; (S)-7,8-Dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b’]dipyran-7-yl 3-Methyl-2-Butenoic Acid Ester; (+)- 7,8-Dihydro-7-hydroxy-8,8-dimethyl-2H,6H-benzo[1,2-b:5,4-b’]dipyran-2-one Ester with 3-methyl-crontonic Acid; 2H,6H-Benzo[1,2-b:5,4-b’]dipyran-2-butenoic Acid Deriv.; (+)-Decursin;
CAS Number:5928-25-6
Molecular Formula:C₁₉H₂₀O₅
Appearance:White to Off-White Solid
Melting Point:110-111°C
Molecular Weight:328.36
Storage:-20°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Decursin is a bioactive metabolites from the root of Angelica gigas Nakai which exhibits neuro-protective and cognitive enhancement effects. Human monoamine oxidase (MAO) inhibitor. Also, it could be useful for the treatment of bone associated with excessive bone resorption.
References:Sowndhararajan, K., et al.: Sci. Pharm., 85, 21/1-21/16 (2017); Lee, H. W., et al.: Int. J. Biol. Macromolec., 97, 598-605 (2017); Weng, X., et al.: Eur. J. Pharmacol., 774, 34-42 (2016)
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