CAS:6055-19-2|Cyclophosphamide Monohydrate

Catalogue Number:C988580
Chemical Name:Cyclophosphamide Monohydrate
Synonyms:N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-Oxide Monohydrate; Cycloblastin; Cyclostin; Cytoxan; Endoxan; Genoxal; Hexadrin; Mitoxan; NSC 26271;
CAS Number:6055-19-2
Alternate CAS #
50-18-0 anhydrous
Molecular Formula:C₇H₁₇Cl₂N₂O₃P
Appearance:White to Off-White Solid
Melting Point:41-450C
Molecular Weight:279.1
Storage:4°C
Solubility:Chloroform (Sparingly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen.This compound is suitable for aldehyde dehydrogenase (ALDH) related research.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References:Wheeler, A.G., et al.: Toxicol. Appl. Pharmacol., 4, 324 (1962), Fraiser, L.H., et al.: Drugs, 42, 781 (1991), Colvin, O.M., et al.: Curr. Pharmaceut. Design, 5, 555 (1999),
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