CAS:618118-95-9|Deamidated Eptifibatide

Catalogue Number:D199895
Chemical Name:Deamidated Eptifibatide
Synonyms:(3R,11S,17S,20S,25aS)-20-((1H-indol-3-yl)Methyl)-17-(carboxymethyl)-11-(4-guanidinobutyl)-1,9,12,15,18,21-hexaoxodocosahydro-1H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosine-3-carboxylic Acid; L-Cysteine N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1→6)-disulfide;Eptifibatide Acid;
CAS Number:618118-95-9
Molecular Formula:C₃₅H₄₈N₁₀O₁₀S₂
Molecular Weight:832.95
Category:Building Blocks; Miscellaneous;
Applications:Deamidated Eptifibatide is a reagent used for synthetic process for solid-phase synthesis of peptides via attachment of cysteinyl thiol to resin. It is an impurity of Eptifibatide (E592000) which is an arginine-glycine-aspartate-mimetic, reversibly binds to platelets to reduce the risk of cardiac ischemic events.
References:Evans, D., et al.: PCT Int. Appl. (2003), WO 2003093301 A2 20031113; Pathak, A., et al.: Cardiovas. Diabetol., 7 (2008), Hantgan, R., et al.: Biochem., 48, 8355 (2009), Giugliano, R., et al.: New Eng. J. Med., 360, 2176 (2009);
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