CAS:629652-40-0|(1S,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloro-acetyl)-2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylic Acid Methyl Ester

Catalogue Number:B121700
Chemical Name:(1S,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloro-acetyl)-2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylic Acid Methyl Ester
Synonyms:(1S,3R)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester; (1S,3R)-1-(1,3-Benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester;
CAS Number:629652-40-0
Molecular Formula:C₂₂H₁₉ClN₂O₅
Appearance:Pale Yellow to Light Brown Solid
Melting Point:>198°C (dec.)
Molecular Weight:426.85
Storage:4°C, Inert atmosphere
Solubility:Chloroform (Slightly), DMSO (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Tryptamines;
Applications:An intermediate in the preparation of cis-Tadalafil (T004520). A PDE5 inhibitor.
References:Beghyn, T. et al.: Bioorg. Med. Chem. Lett., 17, 789 (2007); Daugan, A. et al.: J. Med. Chem., 46, 4533 (2003);
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