CAS:63-89-8|1,​2-​Dipalmitoyl-​sn-​glycero-​3-​phosphocholine (Colfosceril Palmitate)

Catalogue Number:C640500
Chemical Name:1,​2-​Dipalmitoyl-​sn-​glycero-​3-​phosphocholine (Colfosceril Palmitate)
Synonyms:(7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacosan-1-aminium Inner Salt 4-Oxide; 1,2-Bis(hexadecanoyl)-sn-glycero-3-phosphocholine; 1,2-Bis(palmitoyl)-sn-glycero-3-phosphocholine; L-1,2-Dipalmitoylphosphatidyl
CAS Number:63-89-8
Molecular Formula:C₄₀H₈₀NO₈P
Appearance:White to Off-White Solid
Melting Point:>210°C (dec.)
Molecular Weight:734.04
Storage:-20°C, Hygroscopic
Solubility:Chloroform (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Lipids/Fatty Acids, Glycerol Derivatives; Environmental Standards, Mutagens and Metabolites;
Applications:Colfosceril Palmitate is a major phospholipid constituent and primary surface tension lowering component of natural lung surfactant. Colfosceril Palmitate is used as pulmonary surfactant and diagnostic aid (fetal lung maturity).
References:Cha, S., et al.: J. Biol. Chem., 273, 2153 (1998), Pantusa, M., et al.: Biophys Chem., 114, 121 (2005), Pantusa, M., et al.: Eur. Biophys. J., 37, 961 (2008), Lautenslager, G., et al.: Metabolism, 60, 1683 (2011),
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