CAS:67681-86-1|Defluoro-6-chloro Norfloxacin Hydrochloride

Catalogue Number:D228535
Chemical Name:Defluoro-6-chloro Norfloxacin Hydrochloride
Synonyms:6-Chloro-1-ethyl-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride-3-quinolinecarboxylic Acid; Norfloxacin impurity F
Impurity:Norfloxacin impurity F
CAS Number:67681-86-1
Alternate CAS #
free base: 67681-84-9
Molecular Formula:C₁₆H₁₈ClN₃O₃•HCl
Appearance:White to Off-White Solid
Molecular Weight:335.79+36.46
Storage:4°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Defluoro-6-chloro Norfloxacin hydrochloride is impurity F of Norfloxacin (N681000), which is a pefloxacin derivative that acts as a fluorinated quinolone antibacterial.
References:Koga, H., et al.: J. Med. Chem., 23, 1358 (1980), Hirai, K., et al.: Antimicrob. Agents Chemother., 19, 188 (1981), Holmes, B., et al.: Drugs, 30, 482 (1985),
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