CAS:6884-89-5|5-Aminoimidazole-4-carboxamide-1-β-D-Ribofuranosyl 5’-Monophosphate Disodium Salt

Catalogue Number:A612585
Chemical Name:5-Aminoimidazole-4-carboxamide-1-β-D-Ribofuranosyl 5’-Monophosphate Disodium Salt
Synonyms:5(4)-Amino-4(5)-imidazolecarboxamide Riboside 5′-Phosphoric Acid Disodium Salt;Sodium ((2R,3S,4R,5R)-5-(5-Amino-4-carbamoyl-1H-imidazol-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl Phosphate;
CAS Number:6884-89-5
Molecular Formula:C₉H₁₃N₄Na₂O₈P
Appearance:White to Off-White Solid
Melting Point:>204ºC (dec.)
Molecular Weight:382.17
Storage:-20°C
Solubility:Methanol (Slightly), Water (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-Aminoimidazole-4-carboxamide-1-β-D-Ribofuranosyl 5’-Monophosphate Disodium Salt is disodium salt form of 5-Aminoimidazole-4-carboxamide-1-β-D-Ribofuranosyl 5’-Monophosphate (A611705), which causes accumulation of monophosphorylated derivative 5-aminoimidaz ole-4-carboxamide ribonucleoside (ZMP) and consequent phosphorylation and activation of AMP-activated protein kinase (AMPK).
References:Corton, J., et al.: Eur. J. Biochem., 229, 558 (1995); Towler, M., Hardie, D.: Circ. Res., 100, 328 (2007); Narkar, V., et al.: Cell, 134, 405 (2008);
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