CAS:6922-89-0|(4-Chlorophenyl)diphenylmethanol

Catalogue Number:C596465
Chemical Name:(4-Chlorophenyl)diphenylmethanol
Synonyms:4-Chloro-α,α-diphenyl-benzenemethanol; (p-Chlorophenyl)diphenyl-methanol; 4-Chloro-α,α-diphenylbenzenemethanol; 4-Chlorophenyl)diphenylcarbinol; NSC 20739
CAS Number:6922-89-0
Molecular Formula:C₁₉H₁₅ClO
Appearance:Off-white Solid
Molecular Weight:294.77
Storage:20°C, Inert atmosphere
Solubility:Dichloromethane, Ethanol, Ethyl Acetate, Tetrahydrofuran
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(4-Chlorophenyl)diphenylmethanol is an impurity in the synthesis of para-Clotrimazole Isomer (C587405). para-Clotrimazole Isomer (Clotrimazole EP Impurity B) is a positional isomer of the antifungal agent (C587400). It showed agonistic activity on the pregnane X receptor and regulated the levels of apoA1 and HDL-cholesterol in rodents.
References:Buechel, K.H. et al.: Drugs Made Ger., 15, 79 (1972); Bachmann, K. et al.: Pharmacol. Res., 50, 237 (2004)
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