CAS:70380-52-8|2-Amino-5,6-dichloro-3(4H)-quinazolineacetic Acid Methyl Ester Monohydrobromide

Catalogue Number:A604180
Chemical Name:2-Amino-5,6-dichloro-3(4H)-quinazolineacetic Acid Methyl Ester Monohydrobromide
Synonyms:2-Amino-5,6-dichloro-3(4H)-quinazolineacetic Acid Methyl Ester Hydrobromide; Anagrelide Impurity 1 Hydrobromide
CAS Number:70380-52-8
Alternate CAS #
752151-24-9 free base
Molecular Formula:C₁₁H₁₂BrCl₂N₃O₂
Molecular Weight:369.04
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-Amino-5,6-dichloro-3(4H)-quinazolineacetic Acid Methyl Ester is an impurity of Anagrelide (A637300, HCl salt) which is a phosphodiesterase inhibitor with antiplatelet activity.
References:Fleming, J.S., et al.: Thromb. Res., 15, 373 (1979), Seiler, S., et al.: J. Pharmacol. Exp. Ther., 243, 767 (1984), Silverstein, M. N., et al.: N. Engl. J. Med., 318, 1292 (1988), Spencer, C.M., et al.: Drugs, 47, 809 (1994)
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