CAS:7499-07-2|4-Chloro-2-methylbenzoic Acid

Catalogue Number:C427685
Chemical Name:4-Chloro-2-methylbenzoic Acid
Synonyms:4-Chloro-o-toluic Acid; NSC 407521;
CAS Number:7499-07-2
Molecular Formula:C₈H₇ClO₂
Appearance:White Solid
Melting Point:172-173°C
Molecular Weight:170.59
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-Chloro-2-methylbenzoic Acid is used as a reagent in organic synthesis including that of diarylamides which have a pyrimidinyl pyridine scaffold which show promising anti-proliferative effects on melanoma cancer cell lines. It is also used in the preparation of analogs of lenalidomide and pomalidomide for use as anti inflammatory and antitumor agents.
References:Abdelazem, A., et al.: Bioorg. Med. Chem. Lett., 26, 1301 (2016); Ruchelman, A., et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013);
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