CAS:843663-66-1|(aS,bR)-Bedaquiline

Catalogue Number:B119540
Chemical Name:(aS,bR)-Bedaquiline
Synonyms:(αS,βR)-6-Bromo-α-[2-(dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-3-Quinolineethanol
CAS Number:843663-66-1
Molecular Formula:C₃₂H₃₁BrN₂O₂
Appearance:White to Light Yellow Solid
Melting Point:175 – 178°C
Molecular Weight:555.5
Storage:-20°C, Inert atmosphere
Solubility:Chloroform (Slightly), DMF (Slightly), Ethyl Acetate (Slightly), Methanol (Sligh
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(aS,bR)-Bedaquiline is a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.
References:Cheepsattayakorn, A., et al.: Anti-Infect. Drug. Discover.,7, 141 (2012); de Jonge M.R. et al.: Proteins, 67, 971 (2007); Diacon A.H. et al.: N. Eng. J. Med., 360, 2397 (2009);
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