CAS:844499-71-4|A 769662

Catalogue Number:A101205
Chemical Name:A 769662
Synonyms:4-Hydroxy-3-(2′-hydroxy-1,1′-biphenyl-4-yl)-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile; 6,7-Dihydro-4-hydroxy-3-(2′-hydroxy[1,1′-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile
CAS Number:844499-71-4
Molecular Formula:C₂₀H₁₂N₂O₃S
Appearance:Off-White to Beige Solid
Melting Point:263 – 266ºC
Molecular Weight:360.39
Storage:4°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
Category:Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:A 769662 is an AMP-activated protein kinase (AMPK) activiator. A 769662 selectively activates cardiac AMPK heterotrimeric complexes contg. a2/b1-subunits.
References:Timmermans, A.D., et. al.: Am. J. Phys., 306, H1619 (2014)
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