CAS:847158-86-5|(2-Cyclobuten-1-yldimethylsilyl)benzene

Catalogue Number:C990233
Chemical Name:(2-Cyclobuten-1-yldimethylsilyl)benzene
Synonyms:(2-Cyclobuten-1-yldimethylsilyl)-benzene
CAS Number:847158-86-5
Molecular Formula:C₁₂H₁₆Si
Appearance:Colorless Oil
Molecular Weight:188.34
Solubility:Dichloromethane, Ethyl Acetate, Hexane
Category:Building Blocks; Miscellaneous;
Applications:(2-Cyclobuten-1-yldimethylsilyl)benzene is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3b inhibitors as anticancer agents.
References:Choi, M.J., et al.: Bull. Korean. Chem. Soc., 32, 2015 (2011); Otani, M., et al.: Bioorg. Med. Chem. Lett.. 20, 4259 (2010); Jhan, Y.H., et al.: Tetrahedron. Lett., 54, 1155 (2013); Hsieh, J.C., et al.: Org. Biomolec. Chem., 10, 6404 (2012);
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