CAS:850141-19-4|2-epi-Darunavir

Catalogue Number:D193530
Chemical Name:2-epi-Darunavir
Synonyms:TMC 96606; [(1S,2S)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl Ester
CAS Number:850141-19-4
Molecular Formula:C₂₇H₃₇N₃O₇S
Appearance:White to Off-White Solid
Melting Point:99-104°C
Molecular Weight:547.67
Storage:-20°C, Hygroscopic
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Anti-virals/Anti-retrovirals;
Applications:2-epi-Darunavir is a stereoisomer to Darunavir (D193500), a second generation HIV-1-protease inhibitor
References:Rao, R.N., et. al.: J. Sep. Sci., 35, 2671 (2012); Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003); Arasteh, K., et al.: AIDS, 19, 943 (2005); Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005)
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