CAS:850649-62-6|Alogliptin Benzoate

Catalogue Number:A575440
Chemical Name:Alogliptin Benzoate
Synonyms:2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzonitrile Monobenzoate; Nesina; SYR 322; 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzonitrile Benzoate (1:1); (R)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile Benzoate
CAS Number:850649-62-6
Molecular Formula:C₂₅H₂₇N₅O₄
Appearance:White to Pale Grey Solid
Melting Point:180-182°C
Molecular Weight:461.51
Storage:4°C, Inert atmosphere
Solubility:Aqueous Base (Slightly),Chloroform (Slightly), DMSO (Slightly), Methanol (Slight
Category:Standards; Chiral Molecules;
Applications:Alogliptin Benzoate is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Alogliptin Benzoate is used in the treatment of type 2 diabetes.
References:Wang, Y., et. al.: Drugs Future, 33, 7 (2008); Lynn, F., et al.: Diabetes, 50, 1004 (2001); Trumper, A., et al.: J. Endocrinol., 174, 233 (2002); Vollmer, K., et al.: J. Clin. Endocrinol. Metab., 94, 1379 (2009)
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