CAS:859212-16-1|Bafetinib

Catalogue Number:B109050
Chemical Name:Bafetinib
Synonyms:N-[3-([4,5′-Bipyrimidin]-2-ylamino)-4-methylphenyl]-4-[[(3S)-3-(dimethylamino)-1-pyrrolidinyl]methyl]-3-(trifluoromethyl)benzamide; INNO 406; NS 187;
CAS Number:859212-16-1
Molecular Formula:C₃₀H₃₁F₃N₈O
Appearance:Yellow Solid
Melting Point:>166°C (dec.)
Molecular Weight:576.62
Storage:4°C
Solubility:DMSO, Methanol
Category:Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:A substituted benzamide derivative structurally related to STI-571 (Imatinib Mesylate). It was identified as highly potent Bcr-Abl kinase inhibitor. It is a COVID19-related research product.
References:Li, Q., et al.: J. Med. Chem., 39, 3070 (1996), Ptasznik, A., et al.: Nat. Med., 10, 1187 (2004), Tetsuo, A., et al.: Bioorg. Med. Chem. Lett., 16, 1421 (2006),
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