CAS:876322-73-5|4-Amino-2-trifluoromethylbenzaldehyde

Catalogue Number:A876320
Chemical Name:4-Amino-2-trifluoromethylbenzaldehyde
Synonyms:4-Amino-2-(trifluoromethyl)benzaldehyde
CAS Number:876322-73-5
Molecular Formula:C₈H₆F₃NO
Appearance:Beige Solid
Molecular Weight:189.13
Solubility:Methanol, THF
Category:Building Blocks; Miscellaneous;
Applications:4-Amino-2-trifluoromethylbenzaldehyde is an intermediate in the synthesis of N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N’-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea (E926495), which is an inhibitor of RET, FLT3, KDR, c-Abl and c-Kit. Also, it prevent the growth of human thyroid cancer cells.
References:Weisberg, E., et al.: Genes Cancer, 1, 1021-1032 (2010);
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