CAS:885340-12-5|7-Descarboxamido, 7-Cyano (R)-Silodosin O-Benzoate Oxalate

Catalogue Number:C824425
Chemical Name:7-Descarboxamido, 7-Cyano (R)-Silodosin O-Benzoate Oxalate
Synonyms:1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carbonitrile ethanedioate (1:1); (R)-3-(7-Cyano-5-(2-((2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)amino)propyl)indolin-1-yl)propyl benzoate Oxalate
CAS Number:885340-12-5
Alternate CAS #
885340-11-4
Molecular Formula:C₃₂H₃₄F₃N₃O₄ • C ₂H₂O₄
Appearance:White to Off-White Solid
Melting Point:141 – 148°C
Molecular Weight:581.63 + (90.03)
Storage:4°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(R)-3-(7-Cyano-5-(2-((2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)amino)propyl)indolin-1-yl)propyl benzoate Oxalate is an oxalate salt form of 7-Descarboxamido, 7-Cyano (R)-Silodosin O-Benzoate (C824420), which is a silodosin intermediate. Silodosin (S465000) is an a1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertrophy.
References:Li, W., et al.: Faming Zhuanli Shenqing. 7 pp. (2020); Kawabe, K., et al.: BJU Int., 98, 1019 (2006);
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