CAS:895571-80-9|2’-Deoxyguanosine N1-(Ethyl Acrylate)

Catalogue Number:D242435
Chemical Name:2’-Deoxyguanosine N1-(Ethyl Acrylate)
Synonyms:3-[2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6,9-dihydro-6-oxo-1H-purin-1-yl]-2-propenoic Acid Ethyl Ester
CAS Number:895571-80-9
Molecular Formula:C₁₅H₁₉N₅O₆
Molecular Weight:365.34
Category:Standards; Carbohydrates and Oligosaccharides;
Applications:2’-Deoxyguanosine N1-(Ethyl Acrylate) is an intermediate in the synthesis of 3-(2-Deoxy-β-D-erythro-pentofuranosyl)-3,5-dihydropyrimido[1,2-a]purine-6,10-dione (D235185). 3-(2-Deoxy-β-D-erythro-pentofuranosyl)-3,5-dihydropyrimido[1,2-a]purine-6,10-dione is likely an endogenous biomarker in humans and is readily generated from M1dG in liver cytosol, which involves xanthine oxidase and aldehyde oxidase.
References:Otteneder, M.B.; et al.: Proc. Natl. Acad. Sci. U.S.A., 103, 6665 (2006)
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