CAS:900515-16-4|AS-252424

Catalogue Number:A780000
Chemical Name:AS-252424
Synonyms:(5Z)-5-[[5-(4-Fluoro-2-hydroxyphenyl)-2-furanyl]methylene]-2,4-thiazolidinedione
CAS Number:900515-16-4
Molecular Formula:C₁₄H₈FNO₄S
Appearance:Yellow Solid
Melting Point:>235ºC (dec.)
Molecular Weight:305.28
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Very Slightly)
Category:Research Tools; Enzyme Activators and Inhibitors;
Applications:AS-252424 is a novel, potent, and selective phosphoinositide 3-kinase gamma (PI3Kγ) inhibitor. It is also an inhibitor of Casein kinase and PI3K p110a.
References:Pomel, V., et al.: J. Med. Chem., 49, 3857 (2006); Edling, C.E., et al.: Clin. Cancer Res., 16, 4928 (2010); Condliffe, A.M., et al.: Blood, 106, 1432 (2005)
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