CAS:90445-02-6|p-Cl-Amlodipine

CAS:90445-02-6|p-Cl-Amlodipine

Catalogue Number:A633510
Chemical Name:p-Cl-Amlodipine
Synonyms:3-Ethyl 5-methyl Ester 2-[(2-Aminoethoxy)methyl]-4-(4-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid;
CAS Number:90445-02-6
Molecular Formula:C₂₀H₂₅ClN₂O₅
Molecular Weight:408.88
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:p-Cl-Amlodipine is chloro regioisomeric impurity of the drug Amlodipine (A633495). Amlodipine (A633495) is a dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.
References:Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986), Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987), Haria, M., et al.: Drugs, 50, 560 (1995),
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