CAS:915019-52-2|2-(4-((3-Amino-6-bromoquinolin-4-yl)amino)-phenyl)-2-methylpropanenitrile

Catalogue Number:A593845
Chemical Name:2-(4-((3-Amino-6-bromoquinolin-4-yl)amino)-phenyl)-2-methylpropanenitrile
Synonyms:4-[(3-Amino-6-bromo-4-quinolinyl)amino]-α,α-dimethylbenzeneacetonitrile;
CAS Number:915019-52-2
Molecular Formula:C₁₉H₁₇BrN₄
Appearance:Light Beige Solid
Melting Point:>194ºC (dec.)
Molecular Weight:381.27
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Building Blocks; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-(4-((3-Amino-6-bromoquinolin-4-yl)amino)-phenyl)-2-methylpropanenitrile is used as a reagent in the preparation of imidazo quinoline derivatives, compounds that act as mammalian target of rapamycin (mTOR) an phosphatidylinositol 3-kinase (PI3K-kinase) inhibitors.
References:Li, X., et al. Imidazo Quinoline Derivative as mTOR and PI3K-kinase Inhibitor Useful In the Treatment of Various Diseases, and Its Preparation. PCT Int. Appl. 2013053273. Apr 18, 2013.
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