CAS:915087-25-1|4-​Amino-​2-​fluoro-​N-​methylbenzamide

Catalogue Number:A609743
Chemical Name:4-​Amino-​2-​fluoro-​N-​methylbenzamide
Synonyms:N-Methyl-2-fluoro-4-aminobenzamide; 4-amino-2-fluoro-N-methylbenzamide
CAS Number:915087-25-1
Molecular Formula:C₈H₉FN₂O
Appearance:White to Off-White Solid
Melting Point:160 – 163°C
Molecular Weight:168.17
Storage:4°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Stability
Moisture Sensitive
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-​Amino-​2-​fluoro-​N-​methylbenzamide acts as a reagent in the design, synthesis and biological evaluation of novel 5-oxo-2-thioxoimidazolidine derivatives as potent androgen receptor antagonists. Also, in the preparation and structure-activity relationship of chiral benzyloxypyridinone derivatives as c-Met kinase inhibitors
References:Ivachtchenko, A. V., et al.: Eur. J. Med. Chem., 99, 51 (2015); Zhang, D., et al.: Bioorg. Med. Chem. Lett., 23, 2408 (2013)
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