CAS:935666-88-9|AZD 1480

Catalogue Number:A808200
Chemical Name:AZD 1480
Synonyms:5-Chloro-N2-[(1S)-1-(5-fluoro-2-pyrimidinyl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine;
CAS Number:935666-88-9
Molecular Formula:C₁₄H₁₄ClFN₈
Appearance:Pale Beige Solid
Melting Point:>205°C (dec.)
Molecular Weight:348.77
Storage:-20°C, Hygroscopic
Solubility:Chloroform (Slightly, Heated), DMSO (Slightly, Heated), Methanol (Slightly, Heat
Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
Applications:AZD 1480 is an inhibitor of the Jak/Stat Pathway. Potent JAK2 inhibitor.
References:Ioannidis, S., et al.: J. Med. Chem., 54, 262 (2011); Xin, H., et al.: Cancer Res., 71, 6610 (2011);
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