CAS:936491-32-6|N-(2-Chloro-2-methylpropyl)-N-(3,3-diphenylpropyl)-N-methylamine

Catalogue Number:C369905
Chemical Name:N-(2-Chloro-2-methylpropyl)-N-(3,3-diphenylpropyl)-N-methylamine
Synonyms:N-(2-Chloro-2-methylpropyl)-N-methyl-γ-phenyl-benzenepropanamine
CAS Number:936491-32-6
Molecular Formula:C₂₀H₂₆ClN
Molecular Weight:315.88
Category:Building Blocks; Miscellaneous;
Applications:N-(2-Chloro-2-methylpropyl)-N-(3,3-diphenylpropyl)-N-methylamine is a useful synthetic intermediate in the synthesis of Lercanidipine (L179000); a dihydropyridine calcium channel blocker. Antihypertensive.
References:Bianchi, G., et al.: Pharmacol. Res., 21, 193 (1989); Rimoldi, E., et al.: Acta Therap., 200, 23 (1994); Argekar, A., et al.: J. Pharm. Biomed. Anal., 21, 1137 (2000); Rao, A. S., Novel process for the preparation of lercanidipine and its salts. PCT Int. Appl. WO 2007054969. May 18, 2007
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