CAS:936890-98-1|4-(4-Amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f] [1,2,4]Triazin-7-yl)cyclohexanecarboxylic Acid

Catalogue Number:A611910
Chemical Name:4-(4-Amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f] [1,2,4]Triazin-7-yl)cyclohexanecarboxylic Acid
Synonyms:trans-4-[4-Amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]cyclohexanecarboxylic Acid; OSI 027;
CAS Number:936890-98-1
Molecular Formula:C₂₁H₂₂N₆O₃
Appearance:Pale Beige to Light Beige Solid
Melting Point:>149°C (subl.)
Molecular Weight:406.44
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly)
Category:Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:This compound is a kinase inhibitor with anti-tumor activity, used in treatment of breast cancer. Dual mTORC1/C2 inhibitor.
References:Li, H. et al.: Breast Canc. Res. Treat., 134, 1057 (2012);
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