CAS:97614-44-3|2-Deoxy-2-fluoro-a-D-arabinofuranosyl Bromide 3,5-Dibenzoate

Catalogue Number:D235495
Chemical Name:2-Deoxy-2-fluoro-a-D-arabinofuranosyl Bromide 3,5-Dibenzoate
Synonyms:2-Deoxy-2-fluoro-α-D-arabinofuranosyl Bromide Dibenzoate;
CAS Number:97614-44-3
Molecular Formula:C₁₉H₁₆BrFO₅
Molecular Weight:423.23
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;
Applications:2-Deoxy-2-fluoro-a-D-arabinofuranosyl Bromide 3,5-Dibenzoate, can be used in the synthesis of Clofarabine (C586890), which is a second generation purine nucleoside analog. It is also an antimetabolite that inhibits DNA synthesis and resists deamination by adenosine deaminase. Antineoplastic.
References:Yaodong, Y., et al.: Jiefangjun Yaoxue Xuebao, 28, 218 (2012); Gandhi, V., et al.: Clin. Cancer Res., 9, 6335 (2003);
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