CAS:99055-56-8|bis(2-Acetamido-1,3,4-thiadiazol-5-yl) Disulfide

CAS:99055-56-8|bis(2-Acetamido-1,3,4-thiadiazol-5-yl) Disulfide

Catalogue Number:A132750
Chemical Name:bis(2-Acetamido-1,3,4-thiadiazol-5-yl) Disulfide
Synonyms:N,N’-[Dithiobis(1,3,4-thiadiazole-5,2-diyl)]bisacetamide; 2,2′-Dithiobis[5-acetamido-1,3,4-thiadiazole; N,N’-(5,5′-Disulfanediylbis(1,3,4-thiadiazole-5,2-diyl))diacetamide; Acetazolamide Disulphide Impurity:Impurity:Acetazolamide Disulphide Impurity:CAS Number:99055-56-8
Molecular Formula:C₈H₈N₆O₂S₄
Appearance:Off-White to Pale Yellow Solid
Melting Point:277-280°C
Molecular Weight:348.45
Storage:4°C
Solubility:DMSO (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:bis(2-Acetamido-1,3,4-thiadiazol-5-yl) Disulfide is an impurity of Acetazolamide (A161500), a carbonic anhydrase inhibitor. Diuretic. (Acetazolamide Disulphide Impurity)
References:Srinivasu, P., et. al.: J. Pharmaceut. Biomed. Anal., 52, 142 (2010); Vitale, R., et al.: J. Med. Chem., 52, 5990 (2009); Bell, H., et al.: Am. J. Physiol., 297, R370 (2009); Maresca, A., et al.: Bioorg. Med. Chem. Lett., 19, 4929 (2009); Liu, Y., et al.: Anal. Bioanal. Chem., 395, 591 (2009)
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