Cefuroxime Axetil-d3

Chemical Name:Cefuroxime Axetil-d3
Synonyms:(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxy-d3-imino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid 1-(Acetyloxy)ethyl Ester; Altacef-d3; Bioracef-d3; CCI 15641-d3; Cefaks-d3; Cefazine-d3; Ceftin-d3; Cefurax-d3; Cefuroxime-d3 1-Acetoxyethyl Ester; Elobact-d3; Forcef-d3; Oraxim-d3; Zinat-d3; Zinnat-d3;
Alternate CAS #:64544-07-6-unlabelled
Molecular Formula:C₂₀H₁₉D₃N₄O₁₀S
Molecular Weight:513.49
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Labelled Cefuroxime Axetil (C248065). It is the 1-(acetyloxy) ethyl ester of Cefuroxime (C248060), an injectable second generation cephalosporin with an excellent antibacterial activity. This ester has a broader spectrum of activity than cephalexin (first-generation) and is widely used to treat respiratory tract infections. Antibacterial.
References:Nguyen, N., et al.: Pharm. Res., 8, 893 (1991), Stoeckel, K., et al.: Antimicrob. Agents Chemother., 42, 2602 (1998), Scott, L., et al.: Drugs, 61, 1455 (2001), Bulitta, J. B., et al.: Antimicrob. Agents Chemother., 53, 3462 (2009);
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