Dehydroritonavir

Chemical Name:Dehydroritonavir
Synonyms:(3S,4S,6S,9S)-4-Hydroxy-12-methyl-13-[2-(1-methylethenyl)-4-thiazolyl]-9-(1-methylethyl)-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoic Acid 5-Thiazolylmethyl Ester
CAS Number:1156504-13-0
Molecular Formula:C₃₇H₄₆N₆O₅S₂
Molecular Weight:718.93
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Dehydroritonavir is a metabolite of Ritonavir (R535000), a selective HIV protease inhibitor.
References:Yao, M., et. al.: J. Mass Spectrom., 43, 1364 (2008); Li, F., et. al.: Chem. Res. Toxicol., 24, 2109 (2011); Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994); Ammaranond, P., et al.: J. Clin. Virol., 26, 153 (2003); Harrigan, P., et al.: J. Infect. Dis., 191, 339 (2005); Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788(2006)
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