Des-Et-Abemaciclib

Chemical Name:Des-Et-Abemaciclib
CAS Number:1231930-57-6
Molecular Formula:C₂₅H₂₈F₂N₈
Molecular Weight:478.55
Category:Building Blocks; Miscellaneous;
Applications:Des-Et-Abemaciclib is an impurity of Abemaciclib (A115153) is a potent and selective inhibitor of cyclin-dependent kinases, CDK4 and CDK6, as a method to inhibit the proliferation of cancer cells.
References:O’Leary, Ben., et al.: Nat Rev Clin Oncol.,  13, 417 (2016); Van Arsdale., et al.: Clin. Cancer Res., 21, 2905 (2015);
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