Des-(R)-piperidin-3-amine 8-(R)-(Piperidin-3-ylamino) Linagliptin-d3

Des-(R)-piperidin-3-amine 8-(R)-(Piperidin-3-ylamino) Linagliptin-d3

Chemical Name:Des-(R)-piperidin-3-amine 8-(R)-(Piperidin-3-ylamino) Linagliptin-d3
Synonyms:7-(2-Butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-8-[(3R)-3-piperidinylamino]-1H-purine-2,6-dione-d3; (R)-7-(But-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-1H-purine-2,6(3H,7H)-dione-d3
Alternate CAS #:Unlabelled: 1446263-38-2
Molecular Formula:C₂₅H₂₅D₃N₈O₂
Molecular Weight:475.56
Category:Standards; Isotopic Labeled Analogues;
Applications:Des-(R)-piperidin-3-amine 8-(R)-(Piperidin-3-ylamino) Linagliptin-d3 is the labeled analogue of Des-(R)-piperidin-3-amine 8-(R)-(Piperidin-3-ylamino) Linagliptin (D297165), an impurity of Linagliptin (L465900), a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.
References:Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011)
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