Dibenzyl 3-((6-Benzyloxy)-6-oxohexyl)carbamoyl)-3-hydroxypentanedioate

Chemical Name:Dibenzyl 3-((6-Benzyloxy)-6-oxohexyl)carbamoyl)-3-hydroxypentanedioate
Molecular Formula:C₃₃H₃₇NO₈
Molecular Weight:575.65
Category:Building Blocks; Miscellaneous;
Applications:Dibenzyl 3-((6-Benzyloxy)-6-oxohexyl)carbamoyl)-3-hydroxypentanedioate is an intermediate used in the synthesis of 3-[[(5-Carboxypentyl)amino]carbonyl]-3-hydroxypentanedioic Acid (C181165), which is derived from Methyl 6-Aminohexanoate Hydrochloride (M287100), which is used as a reagent to synthesize straight chain hydroxamates, compounds that act as inhibitors of Human Histone Deacetylase (HDAC) that have the potential to treat cancer. Methyl 6-aminohexanoate is also sometimes used as a spacer unit for peptide synthesis.
References:Matthews, S., et al.: J. Chem. Soc. Chem. Commun., 17, 1809 (1995); Remiszewski, S., et al.: J. Med. Chem., 45, 753 (2002)
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