(E)-Cefixime (Cefixime EP Impurity D)

Chemical Name:(E)-Cefixime (Cefixime EP Impurity D)
Synonyms:(6R,7R)-7-[[(2E)-2-(2-Amino-4-thiazolyl)-2-[(carboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; Cefixime E-isomer; [6R-[6α,7β(E)]]-7-[[(2-Amino-4-thiazolyl)[(carboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid;
Impurity
Cefixime EP Impurity D
CAS Number:97164-56-2
Molecular Formula:C₁₆H₁₅N₅O₇S₂
Appearance:Off-White to Pale Yellow Solid
Melting Point:>160°C (dec.)
Molecular Weight:453.45
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(E)-Cefixime is an isomeric impurity of the third generation cephalosporin antibiotic, Cefixime (C242800).
References:Bian, L. et al.: Yao. Fen. Zaz., 30, 872 (2010); Rajadurai, R. et al.: Anal. Chem. Ind. J., 9, 265 (2010);
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