EPPTB

Chemical Name:EPPTB
Synonyms:N-(3-Ethoxyphenyl)-4-(1-pyrrolidinyl)-3-(trifluoromethyl)benzamide; N-(3-Ethoxyphenyl)-4-pyrrolidin-1-yl-3-(trifluoromethyl)benzamide; Ro 5212773
CAS Number:1110781-88-8
Molecular Formula:C₂₀H₂₁F₃N₂O₂
Molecular Weight:378.39
Category:Research Tools;
Applications:EPPTB is a selective antagonist of the trace amine-associated 1 (TA1) receptor, increasing the firing frequency of dopamine (DA) neurons in the ventral tegmental area. This makes it a promising drug target for neurodegenerative disorders.
References:Bradaia, A. et al.: Proc. Nat. Acad. Sci. U.S.A., 106, 10081 (2009);
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