Ethyl 4-(Chlorocarbonyl)-1-piperidinecarboxylate

Ethyl 4-(Chlorocarbonyl)-1-piperidinecarboxylate

Chemical Name:Ethyl 4-(Chlorocarbonyl)-1-piperidinecarboxylate
Synonyms:4-(Chlorocarbonyl)-1-piperidinecarboxylic Acid Ethyl Ester; N-(Ethoxycarbonyl)isonipecotic Acid Chloride
CAS Number:146801-00-5
Molecular Formula:C₉H₁₄ClNO₃
Molecular Weight:219.67
Category:Building Blocks; Miscellaneous;
Applications:Ethyl 4-(Chlorocarbonyl)-1-piperidinecarboxylate, is used as intermediate in the preparation of Risperidone (R525000), which is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.
References:Xuehua, L., et al.: Zhongguo Yaowu Huaxue Zazhi, 17, 89 (2007); Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988);
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