Chemical Name:Fevipiprant
Synonyms:2-Methyl-1-[[4-(methylsulfonyl)-2-(trifluoromethyl)phenyl]methyl]-1H-pyrrolo[2,3-b]pyridine-3-acetic acid; QAW 039; [1-(4-((Methane)sulfonyl)-2-trifluoromethylbenzyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl]acetic acid
CAS Number:872365-14-5
Molecular Formula:C₁₉H₁₇F₃N₂O₄S
Molecular Weight:426.41
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Fevipiprant is used in the oral treatment of asthma and has been successful in targeting severe eosinophilic asthma.Fevipiprant is a novel oral prostaglandin D2 receptor 2 (DP2; known as CRTh2) antagonist and currently in development for the treatment of severe asthma and atopic dermatitis.
References:White, Christobelle., Expert opinion on Investigational Drugs, 427, 199-207, (2018);Pearson, David., Drug Metabolism & Disposition, 45, 817-825, (2017)
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