Forskolin Hemisuccinate-13C4

Chemical Name:Forskolin Hemisuccinate-13C4
Synonyms:1-[(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-Ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-5-yl] Ester Butanedioic Acid-13C4; 1H-Naphtho[2,1-b]pyran Butanedioic Acid Deriv.-13C4;
Alternate CAS #:Unlabelled: 83797-56-2
Molecular Formula:C₂₀¹³C₄H₃₆O₉
Molecular Weight:472.51
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Isotope labelled Forskolin Hemisuccinate is a derivative fo Forskolin (F701800), a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin Hemisuccinate was found to inhibit E-selectin gene transcription through a cAMP-dependent protein kinase pathway.
References:Chersa, P., et al.: J. Biol. Chem., 269, 29129 (1994); Mende, T.J., et al.: Tetrahedron Lett., 31, 5307 (1990); Gupta, P.P., et al.: Indian. J. Pharmacol., 26, 150 (1994);
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