GS-563117

Chemical Name:GS-563117
Synonyms:(S)-5-Fluoro-2-(1-((8-oxo-8,9-dihydro-7H-purin-6-yl)amino)propyl)-3-phenylquinazolin-4(3H)-one
Molecular Formula:C₂₂H₁₈FN₇O₂
Molecular Weight:431.42
Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
Applications:GS-563117 is Idelalisib’s (C124800) metabolite. Idelalisib is a PI3K/mTOR pathway inhibitor used in the treatment of myeloid leukemia through sensitizing the cells to combatting drugs. Potent PI3K-p110-delta inhibitor.
References:Airiau, K. et al.: Cell. Death. Dis., 4, e827 (2013); Kulesz-Martin, M. et al Canc. Biol. Ther., 14m 95 (2013);
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