Isodimethoate (Technical Grade)

Chemical Name:Isodimethoate (Technical Grade)
Synonyms:O,S-Dimethyl S-(2-(Methylamino)-2-oxoethyl) Phosphorodithioate; 2-Mercapto-N-methyl-acetamide S-Ester with O,S-Dimethyl Phosphorodithioate; O,S-Dimethyl S-[2-(Methylamino)-2-oxoethyl] Ester Phosphorodithioic Acid; O,S-Dimethyl Ester, S-Ester with 2-Mercapto-N-methylacetamide Phosphorodithioic Acid;
CAS Number:3344-11-4
Molecular Formula:C₅H₁₂NO₃PS₂
Molecular Weight:229.26
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Isodimethoate is an isomer of Dimethoate (D460505), which is an organophosphate insecticide. Isodimethoate is present in usual pesticide formulations of Dimethoate that is anticholinesterase which disables cholinesterase, an enzyme essential for central nervous system function and thus is neurotoxic for humans. Isodimethoate reacts with human red blood cell acetylcholinesterase (AChE) rendering part of AChE making it non-reactivatable.
References:Tripathy, N.K. et al.: Mut. Res. Gen. Toxicol. Test., 206, 351 (1988); Papp, A. et al.: Pest. Biochem. Physiol., 61, 21 (1998); Eyer, P., et al.: Biochem. Pharmacol., 75, 2045 (2008);
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